Beware! Viruses Are More Deadly When They Infect Their Victims In The Morning

Beware! Viruses Are More Deadly When They Infect Their Victims In The Morning

- in Entertainment, For Health
@Sir. steve
Viruses Are More Deadly When They Infect Their Victims In The Morning
new research by the University of Cambridge suggests that viruses are
more dangerous when they infect their victims in the morning.
According to BBC, the discoveries, published in PNAS, showed viruses were 10 times more successful if the infection started in the morning.
Here is excerpt below as published on BBC Health

And the animal studies found that a disrupted body clock – caused by shift-work or jet lag – was always vulnerable to infection.
The researchers say the findings could lead to new ways of stopping pandemics.
Viruses – unlike bacteria or parasites – are completely dependent on hijacking the machinery inside cells in order to replicate.
But those cells change dramatically as part of a 24-hour pattern known as the body clock.
the study, mice were infected with either influenza, which causes flu,
or herpes virus, which can cause a range of diseases including cold
The mice infected in the morning had 10 times the viral levels of those infected in the evening.
The late viruses were failing after essentially trying to hijack a factory after all the workers had gone home.
Prof Akhilesh Reddy, one of the researchers, told the BBC News website: “It’s a big difference.
virus needs all the apparatus available at the right time, otherwise it
might not ever get off the ground, but a tiny infection in the morning
might perpetuate faster and take over the body.”
He believes the findings could help control outbreaks of disease.
Reddy said: “In a pandemic, staying in during the daytime could be
quite important and save people’s lives, it could have a big impact if
trials bear it out.”
Further tests showed that disrupting the
animal’s body clock meant they were “locked in” to a state that allowed
the viruses to thrive.
Dr Rachel Edgar, the first author, said:
“This indicates that shift workers, who work some nights and rest some
nights and so have a disrupted body clock, will be more susceptible to
viral diseases.
“If so, then they could be prime candidates for receiving the annual flu vaccines.”
The researchers used only two viruses in the study.
the pair were very distinct (one was a DNA virus the other an RNA
virus), which leads the research team to suspect the morning risk may be
a broad principle that applies across a wide number of viruses.
10% of genes, the instructions for running the human body, change
activity throughout the day, and this is controlled by the internal
The research focused on one clock gene called Bmal1, which has its peak activity in the afternoon in both mice and people.
Reddy added: “It’s the link with Bmal1 that’s important, since when
that’s low (in the early morning), you’re more susceptible to
Curiously, Bmal1 becomes less active in people during
the winter months – suggesting it may have a role in the greater risk of
infections at that time of the year.
The body clock has been
implicated in our susceptibility to infections before, flu jabs appear
more effective in morning and jet lag affects the malaria parasite.

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