Alzheimer’s Treatment: Natural and Drugs Treatment for Alzheimer’s

Alzheimer’s Treatment: Natural and Drugs Treatment for Alzheimer’s

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@Sir. steve
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Alzheimer’s is a form of dementia
affecting about millions of individuals across the globe. It is a
progressive type of disorder that gradually worsens over time if timely
treatment is not initiated. In addition, it is also necessary that right
diagnosis be made as the disease manifests no symptoms during its
preliminary stages.
So far there is
no complete cure for Alzheimer’s; however, there are various drugs and
non – drug approaches that can help combat the symptoms and promote
healthy living.

Natural Alzheimer’s Treatment Approach:

There
have been several research trials for studying the efficacy of natural
treatment for Alzheimer’s. Some research studies have pointed towards
the fact that consuming more of nutritious food rich in omega -3 fatty
acids and vitamin E can help prevent cognitive decline. In addition,
there have also been pieces of evidences suggesting that taking herbal
mixtures and vitamin supplements on a daily basis can also help a great
deal in controlling cognitive decline which in a way can be helpful in
Alzheimer’s treatment. However, the efficacy of all these alternative
methods to treat the disease condition is yet to be proved with research
based studies. The National Institute of Health (NIH) has clearly put
forth the fact that so far there has been no clinical evidence
suggesting the effectiveness of these nutrients in Alzheimer’s
treatment.
However,
of late, there has been certain clinical evidence postulating the
effectiveness of an herb named Gingko in treating this disease
condition. This herb is a plant extract that is known to have properties
that can have a beneficial effect in arresting the cognitive decline.
Numerous studies have also confirmed the effectiveness of the Gingko
herb in treating Alzheimer’s. The various symptoms where the herb showed
effect include depression, apathy, listlessness, anxiety, and behavior
during sleeping time. All these symptoms and many showed a more
significant degree of improvement with Gingko plant extract.
Another
substance that has been found to be effective in treating symptoms of
Alzheimer’s is Phosphatidylserine. This substance is involved in the
building the structure and maintenance of cell membranes. Several
clinical trials have confirmed the fact that Phosphatidylserine has
significant positive effects on several symptoms such as depression and
mental decline. Studies have postulated the fact that when about 300 mg
of this substance was taken daily then it showed a great deal of
improvement in cognitive functioning and mental ability of individuals.
Huperzine A is a chemically active compound derived from plant named Huperzia serrata.
This compound is widely available as an over the counter prescription
for memory loss and impairment. However, very few studies have been done
in this regard to prove the efficacy of this drug in Alzheimer’s
treatment.

Alzheimer’s Treatment With Drugs:

Two
types of drug treatment have been approved for Alzheimer’s treatment.
To some extent these drugs are successful in delaying cognitive decline
and also provide help with managing the symptoms. The following list
speaks of the drugs that have been available for treatment of the
disease condition.
1.) Cholinesterase Inhibitors
The
basic cause behind the development of this disease condition is brain
cell atrophy, which inhibits cell – to cell communication.
Cholinesterase inhibitors work by boosting the levels and improve the
cell – to – cell communication. The various drugs in this class are
donepezil, galantamine and rivastigmine. The majority of the individuals
suffering from Alzheimer’s are found to have benefitted from these
drugs. These drugs work by inhibiting the enzyme known as
acetylcholinesterase from breaking down the acetylcholine in the brain.
Due to this, the concentration of acetylcholine increases in the brain,
causing an improvement in the cell – to – cell communication. This in
turn causes a delay in the declining mental capacity and improves the
symptoms. It has also been estimated that about 40 – 60% of individuals
benefit from drugs belonging to cholinesterase inhibitors. It also
requires mention that, this class of drugs. However, does not show any
effect on the behavior changes such as agitation and aggression.
These
drugs also have several side effects such as diarrhea, sleep
disturbance and nausea. It needs mention that the affected individuals
are already suffering from a variety of symptoms and the side effects of
the drugs can increase the burden. But, it has also been found that not
all individuals experience the unpleasant side effects.
2.) Memantine
Memantine
is yet another type of drug that is meant for individuals with moderate
to severe Alzheimer’s disease. This drug slows down the progression of
this disease and the symptoms. Memantine works by blocking the chemical
messenger glutamate – increased concentrations of which causes damage to
the brain cells. In many cases, the doctors may prescribe memantine
with cholinesterase inhibitors.
Guidelines
issued by the National Institute for Health and Clinical Excellence
(NICE) state that cholinesterase inhibitors can even be helpful for
individuals suffering from a severe form of Alzheimer’s disease. It is
also important that, the patients be constantly monitored when they are
put on certain classes of drugs. To understand the side effects and
monitor the effectiveness of the drugs is also a very important task.
Clinical trials are constantly being conducted by scientists across the
globe for searching various new class of drugs that have promising long
term effects for Alzheimer’s treatment.
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